Is Biohyalux Filler from China Dangerous ? How Many Types Are There ? Who Is It Suitable For ?

วันที่อัพเดตล่าสุด : 8 April 2026

Biohyalux Filler

Biohyalux is a Chinese filler brand that has been gaining increasing attention. All of its models are approved by the Thai FDA. However, for many patients, knowing it’s a Chinese-made filler may raise concerns about its effectiveness and safety.
Is Biohyalux filler dangerous ? Why do aesthetic doctors choose to use it ? How does it differ from other filler brands ?

This article explains Biohyalux’s manufacturing technology, how it works, the available models, who it is suitable for, where it can be injected, the expected results after treatment, and whether it is worth the price — all the key information you should know before making a decision.

Table of content : Biohyalux Filler

• What is Biohyalux Filler ?
  • Is Biohyalux Filler Safe ?
• In-Depth Look at Biohyalux Filler Production Technology
• How Does Biohyalux Filler Work ?
• How Many Types of Biohyalux Filler Are There ? What’s the Difference ?
• Where Can Biohyalux Filler Be Injected on the Face ?
• Who Is Biohyalux Filler Suitable For ?
• How Long Does Biohyalux Filler Last ?
• Biohyalux Filler vs. Other Brands
• How Much Does Biohyalux Filler Cost ?
• How to Verify Genuine Biohyalux Filler
• Q&A
  • What are the benefits of Biohyalux Filler ?
  • Are there any side effects from Biohyalux Filler ?
  • Conclusion

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What is Biohyalux Filler ?

BIOHYALUX is a Chinese brand of dermal filler made from Hyaluronic Acid (HA) — a substance that naturally occurs in the human body. As people age, the amount of HA gradually decreases, leading to signs of skin aging such as fine lines, deep wrinkles, and facial sagging. Injecting Biohyalux filler, also known as “Bio Filler,” helps restore volume, smooth out deep wrinkles, enhance facial contours, and boost skin plumpness.

It is a globally trusted filler brand, used by aesthetic doctors in countries such as Poland, Germany, Spain, Turkey, Hungary, China, the Netherlands, Austria, Italy, Greece, Russia, and Thailand. As of 2023, over 8 million syringes have been used worldwide. In Thailand, it is officially imported and distributed by SOE Medical Co., Ltd.

Is Biohyalux Filler Safe ?

Safety is the first priority in filler development. The Hyaluronic Acid (HA) used in Biohyalux Filler is certified by the U.S. FDA and approved by Thailand’s FDA, ensuring it passes strict inspections at every stage.

Biohyalux is produced by Bloomage Biotech, the world’s largest manufacturer of hyaluronic acid, with over 20 years of experience specializing in HA production.

• The company has its own advanced R&D facilities with a team of over 800 researchers.
• Its HA is certified by the U.S. FDA.
• CFDA (China Food and Drug Administration — known for being one of the strictest regulators in the world),
• CE, EDQM, and FDA in more than 12 countries worldwide, including Thailand’s FDA.

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In-Depth Look at Biohyalux Filler Production Technology

Biohyalux Filler is developed using a proprietary technology known as Biobalance Technology (BioBT™) — a unique 1-step crosslinking technique that forms a 3D HA network structure. This structure allows the Hyaluronic Acid to degrade more slowly and retain its shape longer.

The filler is also processed to remain isotonic, which helps preserve cell integrity. Its molecular particles are evenly distributed, leading to minimal swelling or water retention after injection. This ensures precise facial contouring and natural-looking results.

Because of this technology and production process, Biohyalux Filler offers three key advantages:

1. Non-hydrophilic properties that reduce post-injection swelling
2. Immediate, visible results without waiting for swelling to subside
3. Complete biodegradability, leaving no residue in the body for enhanced safety

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How Does Biohyalux Filler Work ?

When Biohyalux Filler is injected into the skin, it quickly integrates with the surrounding tissue to fill deep wrinkles and lines, reducing signs of aging in various areas.

It also restores a youthful appearance by plumping the skin, enhancing hydration, and giving the skin a radiant, dewy look — visibly rejuvenating the face.

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How Many Types of Biohyalux Filler Are There ? What’s the Difference ?

Biohyalux filler is available in 4 different models, all approved by the Thai FDA. Each version comes in a distinctively colored box for easy identification and is formulated with unique characteristics tailored for specific treatment areas.

The choice of model depends on the specific facial area being treated and the expected outcome.

1. BIOHYALUX Fine Line (Blue Box): Developed for correcting superficial skin concerns. It reduces fine lines such as under-eye wrinkles, cheek hollows, and forehead lines, while improving dull skin for a smoother, brighter, and refreshed look.

2. BIOHYALUX LIPS (Pink Box): Designed specifically for lip augmentation. It enhances lip volume naturally, defines the lip contour, hydrates dry lips, and subtly lifts the corners to create a gentle smile.

3. BIOHYALUX DERM LINES (Purple Box): Perfect for treating moderate wrinkles like nasolabial folds, forehead lines, frown lines, brow tails, and crow’s feet. It helps restore smoother, more youthful-looking skin.

4. BIOHYALUX DEEP DERMIS (Gold Box): Best suited for deep dermal lifting and structural enhancement. It is used for nose augmentation, temple filling, chin sculpting, and jawline contouring to achieve a well-defined facial structure.

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Where Can Biohyalux Filler Be Injected on the Face ?

• Under-eye filler
• Temple filler
• Forehead filler
• Malar (apple cheek) filler
• Nose filler
• Chin filler
• Jawline contour filler
• Lip filler
• Lip corner lift filler

Biohyalux filler can be injected into multiple facial areas. Before treatment, a doctor will assess the patient’s skin condition, facial concerns, and budget. The selection also depends on the doctor’s familiarity and experience with the brand.

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Who Is Biohyalux Filler Suitable For ?

• Individuals with sagging skin or deep facial lines
• Those with fine lines and early signs of aging
• People looking to contour and balance their facial features
• Individuals with under-eye hollows or eye bags
• Those wanting to enhance thin lips or improve lip shape
• People seeking plump, hydrated, dewy-looking skin
• Individuals with large pores or acne scars
• Those who wish to enhance facial harmony based on face-reading (feng shui-inspired beauty goals)
  

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How Long Does Biohyalux Filler Last ?

• BIOHYALUX FINE LINES lasts around 6–9 months
• BIOHYALUX LIPS lasts around 6–9 months
• BIOHYALUX DERM LINES lasts around 9–12 months
• BIOHYALUX DEEP DERMIS lasts around 9–12 months

On average, Biohyalux fillers last at least 9 months, depending on the product line and post-treatment care.

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Biohyalux Filler vs. Other Brands

Biohyalux Filler has several distinguishing features:

• Made from high-quality, pure hyaluronic acid (HA)
• Manufactured by Bloomage Biotech, the world’s largest HA producer
• Uses BioBalance Technology, making the filler isotonic — resulting in little to no swelling and very natural-looking results
• Offers 4 product lines for different facial areas
• Results last between 6–12 months
• Certified by the THAI FDA, the US FDA, and regulatory bodies in 12 other countries
• Non-allergenic and leaves no residue in the body

Today’s market includes many filler brands, particularly with new names emerging in the past 2–3 years. Each brand has distinct characteristics. Selecting the right filler depends largely on a doctor’s experience, ensuring treatment is tailored to skin condition and the appropriate filler volume.

Popular Filler Brands Overview:

• Juvederm (USA): Features Hylacross and Vycross technologies; known for smooth texture and versatile product lines covering all facial areas.
• Restylane (Sweden): Uses NASHA and OBT technologies; larger particles offer longer duration and high elasticity — ideal for facial lifting.
• Belotero (Switzerland): Made with CPM technology, known for flexible texture and firmness — great for bone structure and aging correction.
• Definisse (Italy): XTR™ technology forms a 3D HA matrix for natural facial contouring and lifting.
• Flore (Korea): HCCL™ technology creates dense, elastic gel for both structural support and skin hydration.
• Neuramis (Korea): Shape technology provides stability and is suitable for multi-area facial contouring.
• Perfectha (France): E-Brid technology ensures high elasticity and viscosity for long-lasting results.
• Yvoire (Korea): HICE cross-linking gives strong cohesion, perfect for deep dermal injections.
• e.p.t.q. (Korea): 2CM and Downing process tech yield smooth, flexible gel suitable for various facial areas.

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How Much Does Biohyalux Filler Cost ?

The price of Biohyalux Filler starts from 7,xxx THB, which is relatively affordable — similar to Korean fillers. Prices vary by clinic, depending on the number of cc used, and ongoing promotions at the time of treatment

Interested in Biohyalux filler injections at V Square Clinic ?
Click here to view the latest promotions.

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How to Verify Genuine Biohyalux Filler

1. Must include a Thai FDA registration number with accompanying Thai-language documentation.
2. Lot number and manufacturing date must match the information in the QR CODE.
3. Both sides of the box lid have tamper-evident stickers.
4. The front hologram sticker has a QR CODE that can be scanned to verify details such as:

• SOE MEDICAL logo and padlock symbol, stating “This product has not been activated.”
• The clinic that ordered it and the matching QR Code number.
• Clear product image and name, product size, and lot number.
• Manufacturing date, expiry date, and import date (e.g. 20xx-xx-xx).
• Manufacturer: Bloomage Biotechnology Corp., Ltd.
• Importer: SOE Medical Co., Ltd.
• Importer’s address and contact details.

You can verify the lot number with SOE Medical Co., Ltd. at 065-692-8987.

Before undergoing filler injections, always verify that the product is authentic.
Do not rely solely on price when making your decision—counterfeit or unofficially imported fillers may have been stored or transported improperly, which can reduce effectiveness or cause adverse reactions.

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Q&A

What are the benefits of Biohyalux Filler ?

Biohyalux helps lift and contour the face, restoring facial balance with minimal swelling after injection. This allows doctors to shape the face precisely and see immediate results.

Are there any side effects from Biohyalux Filler ?

After injection, mild swelling or redness may occur at the injection site due to the needle, which is normal and resolves on its own.

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Conclusion

Biohyalux Filler has become a popular choice among aesthetic doctors thanks to its reliable manufacturing source, international certifications, wide range of formulations, versatility across injection sites, and ability to deliver natural-looking, immediate results.
(At V Square Clinic, two types are commonly used: Biohyalux Derm Lines and Biohyalux Deep Dermis.)

In addition to Biohyalux, V Square Clinic also offers you a variety of FDA-approved fillers from leading global brands, including Juvederm, Restylane, Belotero, Definisse, Flore, and Neuramis — giving you options that suit different needs, goals, and budgets.

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Reference

• https://www.biohyalux.com/biohyalux
• https://www.soemedical.com/